Mercedes Benz W221 Class S image
Mercedes Benz W221 Class S image
Mercedes Benz W221 Class S image

Mercedes Benz W221 Class S Specs



Choose a Mercedes Benz W221 Class S version from the list below to get information about engine specs, horsepower, CO2 emissions, fuel consumption, dimensions, tires size, weight and many other facts. Notice also the plus sign to access the comparator tool where you can compare up to 3 cars at once side by side.

Key Specs

Production years: from 2005 to 2013
Engine displacement: from 130.8 cu-in / 2143 cm3 to 378.8 cu-in / 6208 cm3
Horsepower: from 201 HP / 204 PS / 150 kW to 621 HP / 630 PS / 463 kW
Length: 200 inches / 508.0 cm Width: 73.62 inches / 187.0 cm Height: 57.87 inches / 147.0 cm Wheelbase: 119.69 inches / 304.0 cm
Curb Weight: from 4023 lbs / 1825 kg to 5016 lbs / 2275 kg
CO2 emissions: from 149 to 355 g/Km


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Petrol Engines

YearHorsepowerEngine displacementCompare with another car
S 350 Specs2005272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 Specs2010272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 4Matic Specs2010272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 4Matic L Specs2010272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 BlueEFFICIENCY Specs2009306 hp / 225 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 BlueEFFICIENCY 4Matic Specs2009306 hp / 225 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 BlueEFFICIENCY 4Matic L Specs2009306 hp / 225 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 BlueEFFICIENCY L Specs2009306 hp / 225 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 L Specs2010272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 350 Long Specs2005272 hp / 200 kW3498 cm3 (213.5 cu-in)Compare with another car
S 450 Specs2006340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 Specs2010340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 4Matic Specs2006340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 4Matic Specs2010340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 4Matic L Specs2010340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 4Matic Long Specs2006340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 L Specs2010340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 450 Long Specs2006340 hp / 250 kW4663 cm3 (284.6 cu-in)Compare with another car
S 500 Specs2005388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 Specs2010388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 4Matic Specs2006388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 4Matic Specs2010388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 4Matic L Specs2010388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 4Matic Long Specs2006388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 BlueEFFICIENCY Specs2009435 hp / 320 kW4663 cm3 (284.6 cu-in)Compare with another car
S 500 BlueEFFICIENCY 4Matic Specs2009435 hp / 320 kW4663 cm3 (284.6 cu-in)Compare with another car
S 500 BlueEFFICIENCY 4Matic L Specs2009435 hp / 320 kW4663 cm3 (284.6 cu-in)Compare with another car
S 500 BlueEFFICIENCY L Specs2009435 hp / 320 kW4663 cm3 (284.6 cu-in)Compare with another car
S 500 L Specs2010388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 500 Long Specs2005388 hp / 285 kW5461 cm3 (333.3 cu-in)Compare with another car
S 600 L Specs2005517 hp / 380 kW5513 cm3 (336.4 cu-in)Compare with another car
S 600 L Specs2009517 hp / 380 kW5513 cm3 (336.4 cu-in)Compare with another car
S 600 L Specs2010517 hp / 380 kW5513 cm3 (336.4 cu-in)Compare with another car
S 63 AMG Specs2006525 hp / 386 kW6208 cm3 (378.8 cu-in)Compare with another car
S 63 AMG Specs2009544 hp / 400 kW5461 cm3 (333.3 cu-in)Compare with another car
S 63 AMG Specs2010525 hp / 386 kW6208 cm3 (378.8 cu-in)Compare with another car
S 63 AMG L Specs2009544 hp / 400 kW5461 cm3 (333.3 cu-in)Compare with another car
S 63 AMG L Specs2010525 hp / 386 kW6208 cm3 (378.8 cu-in)Compare with another car
S 63 AMG Long Specs2006525 hp / 386 kW6208 cm3 (378.8 cu-in)Compare with another car
S 65 AMG L Specs2006612 hp / 450 kW5980 cm3 (364.9 cu-in)Compare with another car
S 65 AMG L Specs2009630 hp / 463 kW5980 cm3 (364.9 cu-in)Compare with another car
S 65 AMG L Specs2010612 hp / 450 kW5980 cm3 (364.9 cu-in)Compare with another car

Diesel Engines

YearHorsepowerEngine displacementCompare with another car
S 250 CDI BlueEFFICIENCY Specs2011204 hp / 150 kW2143 cm3 (130.8 cu-in)Compare with another car
S 250 CDI BlueEFFICIENCY L Specs2011204 hp / 150 kW2143 cm3 (130.8 cu-in)Compare with another car
S 320 CDI Specs2005235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 320 CDI Long Specs2005235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC Specs2009258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC Specs2010258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC 4Matic Specs2009258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC 4Matic L Specs2009258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC L Specs2009258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 BlueTEC L Specs2010258 hp / 190 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 CDI 4Matic Specs2010235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 CDI 4Matic L Specs2010235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 CDI BlueEFFICIENCY Specs2010235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 350 CDI BlueEFFICIENCY L Specs2010235 hp / 173 kW2987 cm3 (182.3 cu-in)Compare with another car
S 420 CDI Specs2006320 hp / 235 kW3996 cm3 (243.9 cu-in)Compare with another car
S 420 CDI Long Specs2006320 hp / 235 kW3996 cm3 (243.9 cu-in)Compare with another car
S 450 CDI Specs2010320 hp / 235 kW3996 cm3 (243.9 cu-in)Compare with another car
S 450 CDI L Specs2010320 hp / 235 kW3996 cm3 (243.9 cu-in)Compare with another car